Case report of Paraproteinemia

Different peripheral neuropathies are linked to paraproteinemia. Anti-myelin-associated glycoprotein (MAG) neuropathy, immunoglobulin or its fragment deposition in the interstitium, light chain amyloidosis (AL amyloidosis) and paraneoplastic mechanisms that cannot be solely attributed deposition, represented by polyneuropathy, organotypic, three main causes of neuropathy correlated with Nerve conduction metrics slow down patients POEMS syndrome anti-MAG neuropathy. An approximately (3.2%) people over age 45-50 have paraproteins their bodies. Plasma cell diseases can thought as a continuum illnesses ranging from asymptomatic myeloma symptomatic monoclonal gammopathy unknown significance (MGUS). A low amount paraprotein (30 g/L), percentage plasma cells bone marrow, absence organ tissue damage characteristics MGUS (predominantly renal, skeletal marrow impairment.) No treatment is necessary for MGUS, there 1% annual risk.